Four New Triterpenoids From Rubus pirifolius Smith.
Four new triterpenoids, pirifoliusic acids B-E, together with seven known compounds (5-11), have been isolated from Rubus pirifolius Smith.
APA
Ning XY, Huang MF, et al. (2026). Four New Triterpenoids From Rubus pirifolius Smith.. Chemistry & biodiversity, 23(2), e03037. https://doi.org/10.1002/cbdv.202503037
MLA
Ning XY, et al.. "Four New Triterpenoids From Rubus pirifolius Smith.." Chemistry & biodiversity, vol. 23, no. 2, 2026, pp. e03037.
PMID
41619287
Abstract
Four new triterpenoids, pirifoliusic acids B-E, together with seven known compounds (5-11), have been isolated from Rubus pirifolius Smith. All these structures were determined by spectroscopic techniques. All the isolated triterpenoids were assessed for cytotoxicity against HL-60 (leukemia), A549 (lung), SMMC-7721 (liver), MDA-MB-231 (breast), and SW480 (colon) cancer cell lines. Among them, compounds 10 and 11 exhibited significant cytotoxicities against these five cancer cell lines.
MeSH Terms
Humans; Triterpenes; Antineoplastic Agents, Phytogenic; Rubus; Cell Line, Tumor; Drug Screening Assays, Antitumor; Molecular Structure; Cell Proliferation; Molecular Conformation; Dose-Response Relationship, Drug