← 뒤로

gene alterations as biomarker in patients with metastatic colorectal cancer treated with FOLFIRI + cetuximab: findings from the CAPRI-2 GOIM study.

1/5 보강

ESMO gastrointestinal oncology 📖 저널 OA 100% 2024~2026 2026 Vol.11() p. 100295

PICO 자동 추출 (휴리스틱, conf 3/4)

P · Population 대상 환자/모집단

7 cases with mutations exhibited limited benefit from treatment with FOLFIRI plus cetuximab with PFS inferior to 8 months.

I · Intervention 중재 / 시술

FOLFIRI/cetuximab as first-line therapy

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

Of note, 6/7 cases with mutations exhibited limited benefit from treatment with FOLFIRI plus cetuximab with PFS inferior to 8 months. [CONCLUSION] Taken together, these results highlight the need to test gene alterations for patients with WT, MSS mCRC, who are candidates for anti-epidermal growth factor receptor therapies.

Ciardiello D, Boscolo Bielo L, Napolitano S, Martinelli E, Troiani T, Cioli E

📖 무료 전문 🟢 PMC 전문 PMC13080806

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

Fatal error: Uncaught PDOException: SQLSTATE[42000]: Syntax error or access violation: 1064 You have an error in your SQL syntax; check the manual that corresponds to your MariaDB server version for the right syntax to use near 'JSON)) ORDER BY n_sources DESC LIMIT 6' at line 3 in /home/prsinsight/public_html/app/core/Database.php:33 Stack trace: #0 /home/prsinsight/public_html/app/core/Database.php(33): PDOStatement->execute() #1 /home/prsinsight/public_html/app/models/WikiPage.php(171): App\Core\Database::fetchAll() #2 /home/prsinsight/public_html/app/views/paper/show.php(671): App\Models\WikiPage::backlinksForPaper() #3 /home/prsinsight/public_html/app/core/View.php(32): include('...') #4 /home/prsinsight/public_html/app/core/View.php(15): App\Core\View->capture() #5 /home/prsinsight/public_html/app/core/Controller.php(21): App\Core\View->render() #6 /home/prsinsight/public_html/app/controllers/PaperController.php(372): App\Core\Controller->render() #7 [internal function]: App\Controllers\PaperController->show() #8 /home/prsinsight/public_html/app/core/Router.php(48): call_user_func_array() #9 /home/prsinsight/public_html/app/core/Router.php(34): App\Core\Router->call() #10 /home/prsinsight/public_html/index.php(282): App\Core\Router->dispatch() #11 {main} thrown in /home/prsinsight/public_html/app/core/Database.php on line 33