Adherence to the EAT-Lancet diet and risk of colorectal cancer in the general population and among individuals with diabetes: a cohort study.
코호트
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
651 participants aged 50–64 without cancer at baseline.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] Higher adherence to the EAT-Lancet diet was associated with lower risk of CRC in middle-aged Danes. [ELECTRONIC SUPPLEMENTARY MATERIAL] The online version of this article (10.1007/s00394-026-03936-6) contains supplementary material, which is available to authorized users.
[BACKGROUND] Healthy and sustainable diets, such as the EAT-Lancet diet, may benefit planetary and human health, though evidence for colorectal cancer (CRC) is limited.
- 추적기간 18.7 years
APA
Rosendal LB, Bundgaard C, et al. (2026). Adherence to the EAT-Lancet diet and risk of colorectal cancer in the general population and among individuals with diabetes: a cohort study.. European journal of nutrition, 65(3). https://doi.org/10.1007/s00394-026-03936-6
MLA
Rosendal LB, et al.. "Adherence to the EAT-Lancet diet and risk of colorectal cancer in the general population and among individuals with diabetes: a cohort study.." European journal of nutrition, vol. 65, no. 3, 2026.
PMID
41801472
Abstract
[BACKGROUND] Healthy and sustainable diets, such as the EAT-Lancet diet, may benefit planetary and human health, though evidence for colorectal cancer (CRC) is limited. This study examined the association between EAT-Lancet diet adherence and CRC risk in middle-aged Danes, including subgroup analysis among individuals with diabetes.
[METHODS] Based on data from the Danish Diet, Cancer, and Health cohort (1993–1997), we included 55,651 participants aged 50–64 without cancer at baseline. Adherence to the EAT-Lancet diet was evaluated using a diet score (0–42 points, 42 indicating highest adherence) from a validated food frequency questionnaire. Cox proportional hazard models were used to estimate hazard ratios (HR) for CRC, colon cancer, and rectal cancer. The pseudo-observation method was used to estimate risk differences after 20 years.
[RESULTS] In total 1877 participants were diagnosed with CRC (median follow-up: 18.7 years). Multivariable-adjusted HRs for CRC, colon cancer, and rectal cancer were 0.75 (95% CI: 0.60, 0.93), 0.73 (95% CI: 0.57, 0.95), and 0.76 (95% CI: 0.50, 1.16) for highest (24–34 points) versus lowest adherence (9–16 points), respectively. The 20-year RD for CRC was -0.60% (95% CI: -1.27, 0.06).
[CONCLUSIONS] Higher adherence to the EAT-Lancet diet was associated with lower risk of CRC in middle-aged Danes.
[ELECTRONIC SUPPLEMENTARY MATERIAL] The online version of this article (10.1007/s00394-026-03936-6) contains supplementary material, which is available to authorized users.
[METHODS] Based on data from the Danish Diet, Cancer, and Health cohort (1993–1997), we included 55,651 participants aged 50–64 without cancer at baseline. Adherence to the EAT-Lancet diet was evaluated using a diet score (0–42 points, 42 indicating highest adherence) from a validated food frequency questionnaire. Cox proportional hazard models were used to estimate hazard ratios (HR) for CRC, colon cancer, and rectal cancer. The pseudo-observation method was used to estimate risk differences after 20 years.
[RESULTS] In total 1877 participants were diagnosed with CRC (median follow-up: 18.7 years). Multivariable-adjusted HRs for CRC, colon cancer, and rectal cancer were 0.75 (95% CI: 0.60, 0.93), 0.73 (95% CI: 0.57, 0.95), and 0.76 (95% CI: 0.50, 1.16) for highest (24–34 points) versus lowest adherence (9–16 points), respectively. The 20-year RD for CRC was -0.60% (95% CI: -1.27, 0.06).
[CONCLUSIONS] Higher adherence to the EAT-Lancet diet was associated with lower risk of CRC in middle-aged Danes.
[ELECTRONIC SUPPLEMENTARY MATERIAL] The online version of this article (10.1007/s00394-026-03936-6) contains supplementary material, which is available to authorized users.