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Advances in the study of nucleolar small RNAs in colorectal cancer.

iScience 2026 Vol.29(3) p. 114789

Yuan Z, Chen Y, Liu S, Yang J, Tang C, He X, Wang S, Wang X

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Colorectal cancer (CRC) is an important public health challenge worldwide, which has led to a continuous search for more precise diagnostic strategies.

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APA Yuan Z, Chen Y, et al. (2026). Advances in the study of nucleolar small RNAs in colorectal cancer.. iScience, 29(3), 114789. https://doi.org/10.1016/j.isci.2026.114789
MLA Yuan Z, et al.. "Advances in the study of nucleolar small RNAs in colorectal cancer.." iScience, vol. 29, no. 3, 2026, pp. 114789.
PMID 41732269

Abstract

Colorectal cancer (CRC) is an important public health challenge worldwide, which has led to a continuous search for more precise diagnostic strategies. Recent studies have revealed that small nucleolar RNAs (snoRNAs) play an important role in CRC. In this article, we first summarize the molecular characteristics and physiological functions of snoRNAs, and then we discuss their mechanisms of action in colorectal carcinogenesis. A key focus is on the emerging potential of snoRNAs as liquid biopsy biomarkers and their prospects for clinical translation in cancer management.

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