Short-and Long-term Patient Outcomes in Hospitals Primarily Serving Patients with Colorectal Cancer from High-Poverty Areas-An Observational Cohort Study.
코호트
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
992 patients with CRC (median age = 78 years, 53.
I · Intervention 중재 / 시술
991 hospitals
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
These findings highlight the presence and negative impact of healthcare segregation by area-level poverty and systemic inequities faced by individuals from HPAs. Multilevel resources are needed to address quality of care and other healthcare-associated needs for individuals from disadvantaged areas.
[BACKGROUND] Prior evidence indicate that differences in treatment settings between patients with colorectal cancer (CRC) from high-poverty areas (HPA, ≥ 20% residents living under poverty level) and
APA
Zheng X, Pinheiro LC, et al. (2026). Short-and Long-term Patient Outcomes in Hospitals Primarily Serving Patients with Colorectal Cancer from High-Poverty Areas-An Observational Cohort Study.. Annals of surgical oncology, 33(4), 3488-3496. https://doi.org/10.1245/s10434-025-18816-2
MLA
Zheng X, et al.. "Short-and Long-term Patient Outcomes in Hospitals Primarily Serving Patients with Colorectal Cancer from High-Poverty Areas-An Observational Cohort Study.." Annals of surgical oncology, vol. 33, no. 4, 2026, pp. 3488-3496.
PMID
41351693
Abstract
[BACKGROUND] Prior evidence indicate that differences in treatment settings between patients with colorectal cancer (CRC) from high-poverty areas (HPA, ≥ 20% residents living under poverty level) and low-poverty areas (LPA) might have contributed to disparities in their health outcomes. We sought to determine whether certain hospitals predominantly provided surgical care for patients with CRC from HPAs and examine associated patient outcomes.
[PATIENTS AND METHODS] We identified patients undergoing surgery for nonmetastatic CRC diagnosed during 1/1/2009-12/31/2019 from SEER-Medicare. We defined poverty-area-serving (PAS) hospitals as hospitals with ≥ 50% patients from HPAs. We compared in-hospital adverse events, 30 day readmission, and long-term mortality between patients from HPAs and LPAs treated at PAS and non-PAS hospitals using logistic and Cox regression.
[RESULTS] Our cohort included 81,992 patients with CRC (median age = 78 years, 53.8% female, 15.9% in HPAs) treated by 991 hospitals. The 180 (18.2%) PAS hospitals treated 64.2% of patients from HPAs versus 2.6% from LPAs. Compared with patients from LPAs treated at non-PAS hospitals, patients from HPAs treated at PAS hospitals had more frequent in-hospital adverse events (OR[95%CI] = 1.17[1.07-1.29]), 30-day readmission (OR[95%CI] = 1.33[1.20-1.47]), worse all-cause (HR[95%CI] = 1.16[1.10-1.22]), and cancer-specific mortality (HR[95%CI] = 1.23[1.15-1.32]).
[CONCLUSIONS] A group of PAS hospitals treated a significant proportion of patients with CRC from HPAs and few from LPAs and was associated with worse short- and long-term patient outcomes. These findings highlight the presence and negative impact of healthcare segregation by area-level poverty and systemic inequities faced by individuals from HPAs. Multilevel resources are needed to address quality of care and other healthcare-associated needs for individuals from disadvantaged areas.
[PATIENTS AND METHODS] We identified patients undergoing surgery for nonmetastatic CRC diagnosed during 1/1/2009-12/31/2019 from SEER-Medicare. We defined poverty-area-serving (PAS) hospitals as hospitals with ≥ 50% patients from HPAs. We compared in-hospital adverse events, 30 day readmission, and long-term mortality between patients from HPAs and LPAs treated at PAS and non-PAS hospitals using logistic and Cox regression.
[RESULTS] Our cohort included 81,992 patients with CRC (median age = 78 years, 53.8% female, 15.9% in HPAs) treated by 991 hospitals. The 180 (18.2%) PAS hospitals treated 64.2% of patients from HPAs versus 2.6% from LPAs. Compared with patients from LPAs treated at non-PAS hospitals, patients from HPAs treated at PAS hospitals had more frequent in-hospital adverse events (OR[95%CI] = 1.17[1.07-1.29]), 30-day readmission (OR[95%CI] = 1.33[1.20-1.47]), worse all-cause (HR[95%CI] = 1.16[1.10-1.22]), and cancer-specific mortality (HR[95%CI] = 1.23[1.15-1.32]).
[CONCLUSIONS] A group of PAS hospitals treated a significant proportion of patients with CRC from HPAs and few from LPAs and was associated with worse short- and long-term patient outcomes. These findings highlight the presence and negative impact of healthcare segregation by area-level poverty and systemic inequities faced by individuals from HPAs. Multilevel resources are needed to address quality of care and other healthcare-associated needs for individuals from disadvantaged areas.
MeSH Terms
Humans; Female; Aged; Colorectal Neoplasms; Male; Survival Rate; Patient Readmission; Follow-Up Studies; United States; Hospitals; Poverty; Aged, 80 and over; Healthcare Disparities; SEER Program; Prognosis; Medicare
같은 제1저자의 인용 많은 논문 (5)
- ASO Visual Abstract: Short- and Long-term Patient Outcomes in Hospitals Primarily Serving Colorectal Cancer Patients from High-Poverty Areas-An Observational Cohort Study.
- PMs-Ti-based plasma extracellular vesicles glycoproteomics and its application in lung cancer.
- E2F1-driven cholesterol synthesis via the SND1/ACLY axis potentiates malignant progression in prostate cancer.
- Icaritin eliminates tumor-associated macrophages via STX16-dependent extracellular vesicle delivery of autophagosomes from hepatocellular carcinoma cells.
- Systematic analysis and mechanistic investigation of cardiac adverse events associated with antibody-drug conjugates using FAERS database.