Annual Review of Systemic Medical Treatment for Colorectal Cancer in 2025.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: BRAF V600E, KRAS mutation, and HER2 amplification
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Precision medicine expanded to patients with BRAF V600E, KRAS mutation, and HER2 amplification. While circulating tumor DNA utility was confirmed for surveillance and guiding rechallenge, its role in real-time treatment adjustment continues to be explored.
This review summarizes landmark advances in colorectal cancer treatment in 2025, characterizing the transition to dynamic precision oncology.
APA
Cai Z, Chen F, et al. (2026). Annual Review of Systemic Medical Treatment for Colorectal Cancer in 2025.. Cancer innovation, 5(2), e70057. https://doi.org/10.1002/cai2.70057
MLA
Cai Z, et al.. "Annual Review of Systemic Medical Treatment for Colorectal Cancer in 2025.." Cancer innovation, vol. 5, no. 2, 2026, pp. e70057.
PMID
41970467
Abstract
This review summarizes landmark advances in colorectal cancer treatment in 2025, characterizing the transition to dynamic precision oncology. Immunotherapy has revolutionized mismatch repair-deficient or microsatellite instability-high patients, becoming the standard first-line and perioperative regimen. Precision medicine expanded to patients with BRAF V600E, KRAS mutation, and HER2 amplification. While circulating tumor DNA utility was confirmed for surveillance and guiding rechallenge, its role in real-time treatment adjustment continues to be explored.
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