Behavioral Interventions Improve Mailed Colorectal Cancer Screening Among Overdue Patients in a Randomized Trial.
무작위 임상시험
3/5 보강
TL;DR
Behaviorally-informed text messaging and mailed reminders significantly increased screening completion, but the health system branded box did not increase response rates.
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
5244 patients included, the mean age was 59.
I · Intervention 중재 / 시술
the box, compared with 18
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] Behaviorally informed text messaging and mailed reminders significantly increased screening completion, but the health system-branded box did not increase response rates. [CLINICALTRIALS] gov, Number: NCT05341622.
OpenAlex 토픽 ·
Colorectal Cancer Screening and Detection
Behaviorally-informed text messaging and mailed reminders significantly increased screening completion, but the health system branded box did not increase response rates.
- p-value P < .001
- 95% CI -2.3 to 1.9
APA
Shivan J. Mehta, Pranay Nadella, et al. (2026). Behavioral Interventions Improve Mailed Colorectal Cancer Screening Among Overdue Patients in a Randomized Trial.. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 24(5), 1442-1451. https://doi.org/10.1016/j.cgh.2025.09.015
MLA
Shivan J. Mehta, et al.. "Behavioral Interventions Improve Mailed Colorectal Cancer Screening Among Overdue Patients in a Randomized Trial.." Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 24, no. 5, 2026, pp. 1442-1451.
PMID
40983155 ↗
Abstract 한글 요약
[BACKGROUND & AIMS] Mailed fecal immunochemical testing (FIT) can boost colorectal cancer screening (CRC) rates, but response rates remain limited. We evaluated if behavioral interventions increased response rates.
[METHODS] This pragmatic randomized trial with a 2 × 2 × 2 factorial design included primary care patients aged 50 to 74 years who were overdue for CRC screening. Patients were randomized 1:1 to receive a health system-branded blue box or a standard envelope. Patients were concurrently randomized 1:1 to receive or not receive text reminders. Patients were also concurrently randomized 1:1 to receive a reminder letter. The primary outcome was the proportion who completed a FIT within 4 months.
[RESULTS] Among 5244 patients included, the mean age was 59.6 years (standard deviation [SD], 7.3 years); 35.8% were Black and 53% were White. At 4 months, 17.8% (95% confidence interval [CI], 16.3%-19.2%) who received the box, compared with 18.0% (95% CI, 16.5%-19.5%) who received the standard envelope, completed FIT, an absolute difference of -0.2% (95% CI, -2.3 to 1.9%; P = .85). Among those who received text messaging, 21.2% (95% CI, 19.6%-22.8%) completed FIT compared with 14.6% (95% CI, 13.2%-15.9%) of those who did not, an absolute difference of 6.6% (95% CI, 4.6%-8.7%; P < .001). Among those that received the mailed reminder, 20.3% (95% CI, 18.7%-21.8%) completed FIT compared with 15.5% (95% CI, 14.1%-16.9%) of those who did not, an absolute difference of 4.8% (95% CI, 2.7%-6.9%; P < .001).
[CONCLUSIONS] Behaviorally informed text messaging and mailed reminders significantly increased screening completion, but the health system-branded box did not increase response rates.
[CLINICALTRIALS] gov, Number: NCT05341622.
[METHODS] This pragmatic randomized trial with a 2 × 2 × 2 factorial design included primary care patients aged 50 to 74 years who were overdue for CRC screening. Patients were randomized 1:1 to receive a health system-branded blue box or a standard envelope. Patients were concurrently randomized 1:1 to receive or not receive text reminders. Patients were also concurrently randomized 1:1 to receive a reminder letter. The primary outcome was the proportion who completed a FIT within 4 months.
[RESULTS] Among 5244 patients included, the mean age was 59.6 years (standard deviation [SD], 7.3 years); 35.8% were Black and 53% were White. At 4 months, 17.8% (95% confidence interval [CI], 16.3%-19.2%) who received the box, compared with 18.0% (95% CI, 16.5%-19.5%) who received the standard envelope, completed FIT, an absolute difference of -0.2% (95% CI, -2.3 to 1.9%; P = .85). Among those who received text messaging, 21.2% (95% CI, 19.6%-22.8%) completed FIT compared with 14.6% (95% CI, 13.2%-15.9%) of those who did not, an absolute difference of 6.6% (95% CI, 4.6%-8.7%; P < .001). Among those that received the mailed reminder, 20.3% (95% CI, 18.7%-21.8%) completed FIT compared with 15.5% (95% CI, 14.1%-16.9%) of those who did not, an absolute difference of 4.8% (95% CI, 2.7%-6.9%; P < .001).
[CONCLUSIONS] Behaviorally informed text messaging and mailed reminders significantly increased screening completion, but the health system-branded box did not increase response rates.
[CLINICALTRIALS] gov, Number: NCT05341622.
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