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Popliteal fossa metastasis from rectal carcinoma in a young adult: A rare case report.

Radiology case reports 2026 Vol.21(6) p. 2444-2448 🔓 OA Colorectal and Anal Carcinomas
OpenAlex 토픽 · Colorectal and Anal Carcinomas Colorectal Cancer Surgical Treatments Cancer Diagnosis and Treatment

Sahi A, Khattak AN, Israr F, Ahmed S, Khalil S, Siddique K

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Signet-ring cell carcinoma (SRCC) of the rectum is a rare and aggressive subtype of colorectal cancer, typically metastasizing to regional lymph nodes, peritoneum, and liver.

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APA Aniqa Sahi, Aruba Nawaz Khattak, et al. (2026). Popliteal fossa metastasis from rectal carcinoma in a young adult: A rare case report.. Radiology case reports, 21(6), 2444-2448. https://doi.org/10.1016/j.radcr.2026.02.012
MLA Aniqa Sahi, et al.. "Popliteal fossa metastasis from rectal carcinoma in a young adult: A rare case report.." Radiology case reports, vol. 21, no. 6, 2026, pp. 2444-2448.
PMID 41889474

Abstract

Signet-ring cell carcinoma (SRCC) of the rectum is a rare and aggressive subtype of colorectal cancer, typically metastasizing to regional lymph nodes, peritoneum, and liver. Metastasis to the popliteal fossa is exceedingly rare. We report a 27-year-old male with biopsy-proven rectal SRCC who developed a painful soft tissue mass in the left popliteal fossa within 1 year despite ongoing chemoradiotherapy. MRI demonstrated a heterogeneous mass with central necrosis, peripheral enhancement, and diffusion restriction. ¹⁸F-FDG PET/CT revealed peripheral FDG avidity (SUVmax 2.8). Ultrasound-guided core biopsy confirmed metastatic adenocarcinoma of colorectal origin. This case highlights an extremely rare metastatic pattern of rectal SRCC and emphasizes the importance of a multimodality imaging approach, including ultrasound, MRI, and PET/CT, in evaluating atypical soft tissue lesions in oncology patients.