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Empyema as an Unusual Presentation of Lung Cancer.

Cureus 2025 Vol.17(11) p. e96674

Arslan F, Khan J, Dhupar A, Kaur N, Amin K, Hussain A

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Malignant empyema is a rare presentation of lung cancer, marked by the accumulation of frank pus in the pleural space.

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APA Arslan F, Khan J, et al. (2025). Empyema as an Unusual Presentation of Lung Cancer.. Cureus, 17(11), e96674. https://doi.org/10.7759/cureus.96674
MLA Arslan F, et al.. "Empyema as an Unusual Presentation of Lung Cancer.." Cureus, vol. 17, no. 11, 2025, pp. e96674.
PMID 41235290

Abstract

Malignant empyema is a rare presentation of lung cancer, marked by the accumulation of frank pus in the pleural space. It can result from various mechanisms, including direct tumor invasion, airway obstruction, immunosuppression, and secondary infections. The clinical presentation is often complex, with symptoms overlapping those of the underlying malignancy and potential complications like sepsis. In the present case, the patient initially presented with chest infection symptoms but, on further investigations, was diagnosed with lung malignancy. Treatment requires a multidisciplinary approach focused on draining the infected fluid, managing infection with antibiotics, and addressing the underlying cancer. Overall, the prognosis of malignant empyema is poor and often fatal.

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