Association of Self-Reported Walking Pace With Cancer Incidence and Mortality: The Women's Health Accelerometry Collaboration.

[BACKGROUND] While the health benefits of walking are well-established, it is not clear if walking pace is associated with cancer-related outcomes.

[PURPOSE] To investigate associations of self-reported walking pace with cancer incidence and mortality among women 62-99 years of age in the Women's Health Accelerometry Collaboration.

[METHODS] Women self-reported walking pace, classified as brisk (≥3 mph), average (2-2.9 mph), casual (<2 mph), or does not walk regularly, and were followed for cancer outcomes. Multivariable stratified Cox proportional hazards models estimated hazard ratios and 95% confidence intervals.

[RESULTS] There were 22,358 women in the analytic sample. During a mean 8.0 years of follow-up, 1891 women developed cancer (n = 615 cancer deaths). Self-reported walking paces were not associated with all site cancer incidence (compared with a brisk walking pace: average walking pace hazard ratio, 1.08 (95% confidence interval, 0.95-1.23); casual walking pace, 1.15 (0.97-1.33), and does not walk regularly 1.14 (0.97-1.34) nor cancer mortality (average walking pace, 0.97 [0.76-1.25], casual walking pace, 0.98 [0.74-1.30], and does not walk regularly 1.20 [0.90-1.60]). Findings were similar when colon, endometrial, and lung cancer were examined, separately. However, casual walking pace was associated with a higher risk of a composite of inactivity-related cancers (1.21 [1.00-1.47]), and breast cancer (1.40 [1.09-1.80]) compared with a brisk walking pace.

[CONCLUSIONS] Slower, compared with faster, self-reported walking paces may be related to a higher risk of some cancers in postmenopausal women. Future research is needed to confirm these findings and investigate mechanisms underlying the associations of walking pace with these cancers.