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Statins attenuate PD-L1 sorting to small extracellular vesicles dependent on ubiquitin-like 3 modification.

1/5 보강

Scientific reports 📖 저널 OA 97.2% 2021~2026 2025 Vol.15(1) p. 43802

PICO 자동 추출 (휴리스틱, conf 2/4)

P · Population 대상 환자/모집단

환자: a high tumor proportion score, serum levels of PD-L1-containing sEVs were significantly lower in those using statins

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

we found that statins, commonly prescribed for hypercholesterolemia, inhibit UBL3 modification, thereby reducing PD-L1 sorting to sEVs.

Ageta H, Shimada Y, Nagaoka T, Takenaka K, Yoshioka Y, Konno K

📖 무료 전문 🟢 PMC 전문 PMC12706078

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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