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Molecular and clinical characteristics of patients with non-small cell lung cancer (NSCLC) harboring KRAS G12V mutations.

1/5 보강
Clinical cancer research : an official journal of the American Association for Cancer Research 📖 저널 OA 54.8% 2022: 3/4 OA 2023: 6/8 OA 2024: 8/14 OA 2025: 57/92 OA 2026: 83/165 OA 2022~2026 2025
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
636 patients with KRAS G12V-mutated NSCLC diagnosed between 2018 and 2023.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] KRAS G12V-mutated NSCLC is characterized by a strong association with tobacco use, high co-mutation rates in clinically relevant genes, and a favorable response to PD-L1-based immunotherapy. The observed mutation landscape supports the potential for dual checkpoint blockade in a significant subset.

John F, Ruge L, Verheyen M, Scharpenseel H, Michels SYF, Riedel R


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