전체 논문 (104편 · 1/4)
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Nanobody Nb07 mitigates sepsis by blocking the PFKM-p53-PD-1 axis to enhance macrophage phagocytosis.
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Tumor cell FAP orchestrates EMT and immune suppression in aggressive localized ccRCC.
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T lymphocyte membrane bionic nanomedicine synergizes with radiotherapy for enhancing Mg-mediated tumor metallo-immunotherapy and preventing recurrence.
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The novel B-cell epitope peptide vaccine, MAX449, exhibits significant anti-tumor efficacy and enhances the therapeutic effects of PD-1 antibodies on tumors by modulating the activity of PMN-MDSCs.
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A cochlea-sparing strategy for non-invasive control of intracranial schwannomas via peripheral irradiation and anti-PD-1 therapy enhanced by STING activation.
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ROS-sensitive liposomal co-delivery of photosensitizer, factor Xa inhibitor, and PD-L1 blockade enhances photodynamic immunotherapy.
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Development of a dendritic cell-targeted vaccine strategy using proximity-induced conjugation.
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Condensatopathies as a mechanistic framework for disease and integrated theranostic intervention.
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Imaging CRISPR-edited CAR-T cell therapies with optical and positron emission tomography reporters.
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Modeling immunotherapies in live 3D human cancer tissue bioreactors.
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Lactylation-driven -mediated RNA m5C modification promotes perineural invasion in pancreatic cancer.
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OSBPL3-driven sterol metabolic reprogramming promotes oncogenic signaling and therapeutic resistance in pancreatic cancer.
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One-step knock-in CAR constructs in human NK cells enable scalable, TGFβ1-resistant immunotherapy for solid tumors.
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Enhancer-mediated NR2F2 recruitment activates BGN to promote tumor growth and shape tumor microenvironment in papillary thyroid cancer.
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CD45⁺ hybrid circulating cells may reflect tumor-immune interactions and serve as transcriptomic indicators of metastatic potential in prostate cancer.
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Targeting CAMK1D-engineered nanoactivator suppresses cancer stem cell maintenance and immune evasion in enzalutamide-resistant prostate cancer.
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Optimizing PSMA-617-based inhibitors through charged linker modifications: Insights into structure-activity relationships.
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Characterization and validation of a bone metastatic castration-resistant prostate cancer model as a nanomedicine evaluation platform.
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PSMA-targeted fluorescent probe for NIR-II imaging in prostate cancer intraoperative navigation and tumor margin mapping.
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Phase I dose-escalation study of [¹⁷⁷Lu]Lu-LNC1011, a long-circulating dansyl-modified PSMA theranostics, in metastatic castration-resistant prostate cancer.
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Mitochondria-specific targeting of noncanonical ntmRNA-coordinated mitophagy receptor BNIP3 homodimerization disrupts mitochondrial metabolism and suppresses hepatocellular carcinoma growth and .
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Verteporfin-loaded hydrogel targeting YAP-mediated MDSCs recruitment for the treatment of residual tumors after incomplete radiofrequency ablation.
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Targeting the ARL4C/RAP1/PI3K-Akt-mTOR signaling loop promotes ARL4C ubiquitination and reverses oxaliplatin resistance in colorectal cancer.
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Single-cell RNA sequence analysis reveals USP32 as a therapeutic target to mitigate PD-L1-driven colorectal tumorigenesis and .
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A novel whole cancer cell vaccine based on modified β-glucan elicits robust anti-tumor immunity.
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PLK1 stabilizes β-catenin to drive colorectal carcinogenesis through NFKB2-mediated transcriptional activation of USP2a and site-specific phosphorylation.
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Multimodal tumor thermal therapy enhances antitumor immunity by expanding tumor-reactive CX3CR1⁺GPR56⁺ T cells in hepatocellular carcinoma.
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Early diagnosis of colorectal cancer using Cerenkov luminescence endoscopy: a pilot trial involving humans for the first time.
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Context-dependent Activities of Mitrephorone Link Lipid Redirection, Anti-inflammatory Action, and Ferroptosis Control to Hepatocyte Protection.
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Identification of programmed cell death-related subtypes reveals immune heterogeneity and therapeutic divergence in colon cancer.