전체 논문 (121편 · 1/5)
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Activation of T Cell-Intrinsic p53 by Acetylation Elicits Antitumor Immunity to Boost Cancer Immunotherapy.
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Single-cell spatial atlas of high-grade serous ovarian cancer uncovers MHC class II as a key predictor of spatial tumor ecosystems and clinical outcomes.
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A Circulating GPNMB-Based Multimodal Model Integrates Tumor-Immune Crosstalk to Predict Immunotherapy Response in Esophageal Cancer.
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Molecular and Immune Correlates of Response to First-Line De-escalated Chemotherapy plus Penpulimab and Anlotinib in Advanced Cervical Cancer.
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Dual Targeting of TGFβ1 and PD-1 Is Safe and Tolerable in Solid Tumors.
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Personalized Cancer Vaccine Shows Durable Benefit at 5 Years.
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Neoadjuvant BO-112 and hypofractionated radiation therapy with or without nivolumab in soft tissue sarcoma: preclinical and phase 1 results.
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HIF-2α Inhibitor Combinations Knock Back Kidney Cancer in Two Trials.
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Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.
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Arachidonic Acid Metabolism in PMN-MDSCs Suppresses Antitumor Capacity of T cells in KRAS-Mutant Cholangiocarcinoma.
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Intratumoral sotigalimab with pembrolizumab induces rapid activation of antigen presenting cells and drives anti-tumor responses in non-injected tumors in metastatic melanoma: A phase I/II study.
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Pharmacological inhibition of PMS2 induces MMR deficiency and response to immune checkpoint blockade.
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Cellular neighborhoods govern antitumor T-cell infiltration following anti-CTLA-4 in melanoma with primary resistance to anti-PD-1.
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Phase III Data Support Chemo-Free Approach to ALL.
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Study Backs MRD as AML Trial Endpoint.
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Multidimensional Characterization of Tumor-Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma Subtypes.
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New BTK Inhibitors May Combat Resistance in CLL.
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Epcoritimab Combo Could Be New Standard for Some FLs.
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Cancer Throughlines: 25 Years after First Approval, ADCs Continue to Pick up Steam.
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DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML but Is Associated with Increased Leukemia Stem Cell Frequency.
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Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia.
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Base Editing Might Be Key to CAR T-cell Therapy.
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Early Driver, Late Bystander: Stage-Specific Roles of DNMT3A R882 Mutations Unveiled in Human AML.
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Same-Slide Spatial Multi-Omics Integration with IN-DEPTH Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment.
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Trends in Childhood and Adolescent Cancer Incidence Rates in the United States between 2001 and 2022.
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IL1RAP antibody-drug conjugates potently target primary and metastatic disease in multiple oncofusion-driven cancers.
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SPEN loss drives extra-follicular diffuse large B cell lymphoma with female-specific lethality and therapeutic vulnerabilities.
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Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization.
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Development and Prospective Validation of a Cell-free DNA-Based Model for the Early Detection of Pancreatic Cancer.
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Cigarette Smoke Skews T Cells to Promote Pancreatic Cancer.