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3건-
Development and validation of a nomogram model for predicting postoperative delirium in elderly patients with oral cancer: a retrospective study.
[OBJECTIVE] This study aimed to develop and internally validate a dynamic a nomogram model by analysing the risk factors for postoperative delirium (POD) in elderly patients with oral cancer. [METHODS] This was a single-centre, retrospecti…
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Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
[OBJECTIVE] Inflammation is central to the development and progression of diabetic nephropathy (DN). Although the exact mechanisms of inflammation in the kidney have not been well elucidated, pyrin domain containing 3 (NLRP3) inflammasome a…
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Ras-Related C3 Botulinum Toxin Substrate 1 Combining With the Mixed Lineage Kinase 3- Mitogen-Activated Protein Kinase 7- c-Jun N-Terminal Kinase Signaling Module Accelerates Diabetic Nephropathy.
Ras-related C3 botulinum toxin substrate 1 (RAC1) activation plays a vital role in diabetic nephropathy (DN), but the exact mechanism remains unclear. In this study, we attempted to elucidate the precise mechanism of how RAC1 aggravates DN …