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Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway.
Exposure of articular cartilage to excessive mechanical loading is deeply involved in the pathogenesis of osteoarthritis. Here, we identify gremlin-1 as a mechanical loading-inducible factor in chondrocytes, detected at high levels in middl…
- Color chart pasted on diascope for objective evaluation of color and size.