논문 목록
7건-
A multidimensional pan-cancer analysis of CD47 and its role in promoting malignant phenotype in pancreatic adenocarcinoma.
[BACKGROUND] CD47 is a widely expressed member of the immunoglobulin superfamily and plays important roles in cell proliferation, adhesion, and immune evasion. Previous studies have shown that CD47 contributes to tumor development by inhibi…
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Identification of the disulfidptosis-related gene G6PD as a potential biomarker and therapeutic target in pancreatic ductal adenocarcinoma by integrative bioinformatics analysis and experimental validation.
[BACKGROUND] Pancreatic adenocarcinoma (PAAD) is a highly lethal digestive system tumor with a low five-year survival rate and limited treatment efficacy, underscoring the need for new therapeutic targets. Disulfidptosis, a novel cell death…
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Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation.
[BACKGROUND] The role of copper-induced cell death, termed cuproptosis, has been demonstrated recently. Nonetheless, the potential biological function of cuproptosis regulators in thyroid cancer (THCA) remains unknown. [METHOD] We analyzed…
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Signet-ring cell cytomorphology in breast cancer: Unveiling the overlooked.
Signet-ring cell (SRC) cytomorphology in breast carcinomas involves cells distinguished by copious intracellular mucin that displaces the nucleus, imparting a characteristic signet-ring appearance. Although SRC terminology is prevalent with…
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ATF6 and pS6K as prognostic biomarkers in newly diagnosed diffuse large B-cell lymphoma.
This study aimed to investigate the clinical and prognostic significance of activating transcription factor 6 (ATF6) and phosphorylated S6 kinase (pS6K) expression in newly diagnosed diffuse large B-cell lymphoma (DLBCL). We conducted a ret…
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Early Initiation of Dangle Protocol in Lower Extremity Free Flap Microsurgery.
Defects of the lower extremity often require free tissue transfer to provide adequate soft tissue reconstruction. Patients typically undergo a postoperative dangle protocol to condition the flap to withstand the increase in venous pressure.…
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Three Cases of Bilateral Breast Absence Associated with Familial Congenital Ectodermal Defects.
[OBJECTIVE] This study aims to analyze three cases of bilateral breast absence associated with congenital ectodermal defects in the same family to identify a suitable clinical treatment plan. [METHODS] Three patients (case 1 and case 2 are…