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11건 · 최신순-
Botulinum toxin use in patients with neurological disorders: A U.S.-based claims database analysis.
[BACKGROUND AND OBJECTIVE] Real-world evidence describing long-term persistency with botulinum toxin (BoNT) therapy is limited. We assessed treatment patterns and persistency with BoNT in clinical practice over 2 years. [DESIGN] Retrospect…
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Review: Botulinum Toxin for Treatment of Focal Limb Dystonia.
Focal limb dystonias (FLDs) are abnormal postures and muscle contractions in an arm or leg that can occur in the setting of specific activities or without any stimulus. This pathology can have a profound impact on quality of life and potent…
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A modified scoping review of interventions for global post stroke spasticity.
[PURPOSE] Stroke is a major global health concern, and post-stroke spasticity (PSS) can severely impair mobility and quality of life. This modified scoping review synthesizes the most current evidence up to 2024 for interventions targeting …
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Effectiveness, safety, and quality of life outcomes of neurotoxin injections in the treatment of essential tremors: a systematic review.
Essential tremor (ET) is a chronic, progressive condition classically affecting the hands and arms, is typically bilateral, and may be asymmetric. Tremor related disability can impact mood and quality of life. Disease progression and patien…
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Best Practice Guidelines for the Management of Patients with Post-Stroke Spasticity: A Modified Scoping Review.
This article aims to provide a concise overview of the best available evidence for managing post-stroke spasticity. A modified scoping review, conducted following the PRISMA guidelines and the PRISMA Extension for Scoping Reviews (PRISMA-Sc…
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Comparison of Ultrasound and Electrical Stimulation Guidance for Onabotulinum Toxin-A Injections: A Randomized Crossover Study.
[BACKGROUND] Botulinum neurotoxin (BoNT) injection is an established therapy for limb spasticity and focal limb dystonia. Comparative benefits of injection guidance procedures have not been rigorously studied. [OBJECTIVES] We compared 2 ta…
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Pain Reduction in Adults with Limb Spasticity Following Treatment with IncobotulinumtoxinA: A Pooled Analysis.
Some studies have shown that incobotulinumtoxinA reduces spasticity-associated pain, but further evidence is needed. This exploratory analysis pooled pain-relief data from six Phase 2 or 3 studies of incobotulinumtoxinA (four placebo-contro…
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Botulinum Toxin Therapy in Writer's Cramp and Musician's Dystonia.
Task-specific focal dystonia is characterized by muscle contraction(s) during a specific task, resulting in abnormal postures or movements. Specifically, writer's cramp involves the upper extremity during the act of writing. Musician's dyst…
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Tolerability and Efficacy of Customized IncobotulinumtoxinA Injections for Essential Tremor: A Randomized, Double-Blind, Placebo-Controlled Study.
In this first, double-blind, randomized, placebo-controlled exploratory trial, we evaluate the efficacy and safety of incobotulinumtoxinA and feasibility of using kinematic tremor assessment to aid in the planning of muscle selection in a m…
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Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity.
Poststroke spasticity affects up to one-half of stroke patients and has debilitating effects, contributing to diminished activities of daily living, quality of life, pain, and functional impairments. Botulinum toxin (BoNT) is proven to be s…
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Effects of mandibular orthognathic treatment on mucogingival tissues.
Twenty-four patients receiving comprehensive orthognathic care including genioplasty were studied to evaluate the effect of orthognathic treatment on the mucogingival complex in the mandibular anterior region. Parameters measured prior to a…