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Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor.
DNAX-associated protein 12 kD size (DAP12) is a dominant immunoreceptor tyrosine-based activation motif (ITAM)-signaling adaptor that activates costimulatory signals essential for osteoclastogenesis. Although several DAP12-associated recept…
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The Zebrafish Cerebellar Neural Circuits Are Involved in Orienting Behavior.
Deficits in social behavior are found in neurodevelopmental disorders, including autism spectrum disorders (ASDs). Since abnormalities in cerebellar morphology and function are observed in ASD patients, the cerebellum is thought to play a r…
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Soft-tissue reconstruction after soft-tissue sarcoma resection: the clinical outcomes of 24 patients.
[PURPOSE] Pedicle or free-flap reconstruction is important in surgical sarcoma management. Free flaps are indicated only when pedicle flaps are considered inadequate; however, they are associated with a higher risk of flap failure, longer s…
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Retrosigmoid Approach in the Supine Position Using ORBEYE: A Consecutive Series of 14 Cases.
One of the merits of recently introduced exoscopes, including ORBEYE, is that they are superior to a conventional microscope in terms of ergonomic features. Taking advantage of it, the retrosigmoid approach can be performed in the supine po…
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Four Hands Surgery for Intracerebral Hemorrhage using Orbeye: Educational Values and Ergonomic Advantages - A Technical Note.
We have developed a new educational approach to microsurgery in which a trainee and supervisor can cooperate with "4 hands" using the exoscope. We evaluated 4-hands surgery for intracranial hemorrhage (ICH) using the exoscope to validate th…
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Involvement of Cerebellar Neural Circuits in Active Avoidance Conditioning in Zebrafish.
When animals repeatedly receive a combination of neutral conditional stimulus (CS) and aversive unconditional stimulus (US), they learn the relationship between CS and US, and show conditioned fear responses after CS. They show passive resp…
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Microsurgery "Under the Eaves" Using ORBEYE: A Case of Dural Arteriovenous Fistula of the Anterior Cranial Fossa.
[BACKGROUND] One of the merits of exoscopes, including ORBEYE, is that they are superior to a microscope in terms of ergonomic features. We report a case of dural arteriovenous fistula (dAVF) that was cured by direct surgery using the ergon…
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Granule cells control recovery from classical conditioned fear responses in the zebrafish cerebellum.
Although previous studies show that the cerebellum is involved in classical fear conditioning, it is not clear which components in the cerebellum control it or how. We addressed this issue using a delayed fear-conditioning paradigm with lat…
- [Dermatoplasty for extensive scalp defect (author's transl)].