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15건 · 최신순-
Timing of Thickened Liquid Intake After Tongue and Floor-of-Mouth Tumour Reconstruction: A Randomised Controlled Trial.
[OBJECTIVE] This study aimed to determine the optimal timing and viscosity of thickened liquid intake for patients undergoing tongue and floor-of-mouth tumour resection with reconstruction, using VFSS to reduce nasogastric tube dependence, …
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Botulinum Toxin Type A Inhibits Submandibular Secretion via the ERK/miR-124-3p/Specificity Protein 1/Claudin-1 Axis.
Botulinum toxin type A (BTXA) is widely used for the treatment of sialorrhea; however, its mechanism remains unclear. Tight junctions (TJs) are limiting factors for salivary secretion through the paracellular pathway in the salivary gland, …
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Reconstruction of the anterior maxillary defect using a vascularized bone flap with residual teeth in the posterior maxilla.
[BACKGROUND] Microsurgical bone reconstruction is challenging in cases of anterior maxillary defects because of the presence of residual teeth. The study analyzed the method and feasibility of using vascularized bone flaps to reconstruct an…
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Early swallowing training after free flap surgery in oral cancer: A randomized controlled trial.
[OBJECTIVE] To explore the effect of early swallowing training on postoperative outcomes of patients who had undergone oral cancer surgery plus free flap reconstruction. [SUBJECTS AND METHODS] In this prospective, randomized controlled tri…
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Effects of personalized oral exercises on swallowing function among patients with oral cancer after free flap transplantation: a cluster randomized controlled trial.
Dysphagia is a common complication in patients with oral cancer who have undergone free flap transplantation. The aim of this cluster randomized controlled trial was to evaluate the effect of personalized oral exercises on swallowing functi…
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Retrospective study of the deep circumflex iliac artery flap and the vascularized fibula free flap for maxillary defect repair.
[OBJECTIVES] The deep circumflex iliac artery flap (DCIA) and vascularized fibular free flap (FFF) are mainstay flaps for maxillary defect reconstruction. This study compared the functional outcomes and success rates of these flaps to provi…
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Botulinum toxin type A inhibits M1 macrophage polarization by deactivation of JAK2/STAT1 and IκB/NFκB pathway and contributes to scar alleviation in aseptic skin wound healing.
The non-neuronal and non-muscular effects of botulinum toxin type A (BTXA) on scar reduction has been discovered. This study was designed to investigate the effects of BTXA on macrophages polarization during the early stage of skin repair. …
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Timing of Oral Feeding in Patients Who have Undergone Free Flap Reconstruction for Oral Cancer.
[OBJECTIVE] Determine the safety and effectiveness of a nasogastric tube removal plan designed to shorten nasogastric tube indwelling time after oral cancer surgery plus free flap reconstruction. [MATERIALS AND METHODS] A parallel randomiz…
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Preoperative oral carbohydrates in elderly patients undergoing free flap surgery for oral cancer: randomized controlled trial.
The aim of this study was to evaluate the safety of carbohydrate intake 2 hours before surgery in elderly patients undergoing free flap surgery for oral cancer. Elderly patients undergoing free flap surgery between September 2019 and Januar…
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Effects of personalized swallowing rehabilitation in patients with oral cancer after free flap transplantation: A cluster randomized controlled trial.
[OBJECTIVES] Dysphagia is a common and serious complication in patients with oral cancer after free flap transplantation (OC-FFT), which seriously affects their quality of life. Studies have found swallowing rehabilitation can improve the s…
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Botulinum toxin A treatment of epiphora secondary to autologous submandibular gland transplantation.
The aim of this study was to explore whether botulinum toxin A (BTXA) injection treats epiphora secondary to submandibular gland (SMG) transplantation for severe keratoconjunctivitis sicca. Fifteen patients with epiphora after SMG transplan…
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Botulinum toxin type A interrupts autophagic flux of submandibular gland.
Botulinum toxin type A (BTXA) is a neurotoxic protein produced by Our previous studies demonstrated that BTXA inhibits the secretory function of submandibular gland (SMG) and changes its structure. Several studies reported that SMG damage …
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An Experimental Study on Botulinum Toxin Type A for the Treatment of Excessive Secretion after Submandibular Gland Transplantation in Rabbits.
. To investigate whether botulinum toxin type A (BTXA) could control excessive secretion after submandibular gland (SMG) transplantation in rabbits and its possible mechanisms. . A new SMG transplantation model was established in rabbit. 30…
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Pre- and Post-synaptic Effects of Botulinum Toxin A on Submandibular Glands.
Intraglandular injection of botulinum toxin type A (BoNT/A) is an effective treatment for sialorrhea. Despite numerous experimental and clinical studies on inhibition of saliva section by BoNT/A, the proteolysis of synaptosomal-associated p…
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Efficacy and safety of botulinum toxin type A for treatment of Frey's syndrome: evidence from 22 published articles.
Frey's syndrome (FS) is an unavoidable sequela following the surgery of the parotid gland. Although several treatment methods are available, their efficacy is short term or accompanied by unacceptable complications. In the past two decades,…