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SMARCA4-Deficient Undifferentiated Thoracic Tumor: Clinical Features and Prognosis of a Case Series and Literature Review.
[INTRODUCTION] Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UT) are rare and aggressive epithelioid neoplasms characterized by the loss of the SMARCA4 gene. These tumors are typically diagnosed at advanced stages and exhibit …
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Integrating transcriptomic and metabolomic analyses to characterize the potential function of SLC1A5 in thyroid cancer.
[BACKGROUND] Alanine Serine Cysteine transporter 2 (ASCT2/SLC1A5) is a key glutamine transporter in cancer cells and has been shown in a variety of cancers to promote tumor growth by reprogramming glutamine metabolism and altering the tumor…