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Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review.
ImportanceThere is a limited understanding of anterior commissure (AC) involvement in glottic squamous cell carcinoma (SCC), particularly when comparing T1b, T2a with AC involvement (T2AC), and T2a without AC involvement (T2noAC).ObjectiveT…
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Oncologic and Functional Outcomes of T3 Glottic Squamous Cell Carcinoma Following Transoral Laser Microsurgery: A Retrospective Chart Review.
ImportanceFew centers globally use transoral laser microsurgery (TLM) for primary treatment of T3 glottic squamous cell carcinoma (SCC); consequently, data on its use in this setting are sparse.ObjectiveThe aim of this study was to evaluate…
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"Close Then Clear" Margins in Transoral Resection of p16+ Oropharyngeal Squamous Cell Carcinoma.
[OBJECTIVE] Standard 5-mm surgical margins in the oropharynx are challenging due to the intimate relationship with neurovascular structures and patient function. De-escalation of therapy with the acceptance of close surgical margins may imp…
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Five-year survival outcomes in oropharyngeal squamous cell carcinoma following transoral laser microsurgery.
[OBJECTIVE] To determine the 5-year survival outcomes of patients with oropharyngeal cancer treated with transoral laser microsurgery at our institution. [METHODS] A prospective longitudinal cohort study of all cases of oropharyngeal squam…
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Oncological and functional outcomes following treatment of T1a glottic squamous cell carcinoma with transoral laser microsurgery.
[BACKGROUND] Laryngeal cancers of glottic origin comprise a large proportion of head and neck malignancies. Transoral laser microsurgery (TLM) and radiation therapy are mainstays in the treatment of early stage glottic cancer, but debate pe…
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Injection laryngoplasty during transoral laser microsurgery for early glottic cancer: a randomized controlled trial.
[BACKGROUND] Transoral laser microsurgery is widely used for treating T1/T2 glottic cancers. Hyaluronic acid (HA) is commonly used in vocal cord augmentation. We investigated the impact of intra-operative injection laryngoplasty on voice ou…
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Functional and Oncologic Outcomes of Octogenarians Undergoing Transoral Laser Microsurgery for Laryngeal Cancer.
[OBJECTIVE] To evaluate the oncologic and functional outcomes of transoral laser microsurgery (TLM) for glottic cancers in patients ≥80 years. [STUDY DESIGN] Prospectively collected case series. [SETTING] QEII Health Sciences Centre, Hali…
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Oncological and functional outcomes after repeat transoral laser microsurgery for the treatment of recurrent early glottic cancer.
[BACKGROUND] Transoral laser microsurgery for glottic squamous cell carcinoma is the standard of care at many institutions. Repeat transoral laser microsurgery for recurrence may avoid the need for radiotherapy and total laryngectomy. This …
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Intraoperative Primary Tumor Identification and Margin Assessment in Head and Neck Unknown Primary Tumors.
[OBJECTIVE] Surgical management of the unknown primary head and neck squamous cell carcinoma (UP HNSCC) remains controversial due to challenging clinical diagnosis. This study compares positron emission tomography-computed tomography (PET-C…
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Tubed Anterolateral Thigh Free Flap for Pharyngoesophageal Reconstruction.
Caustic ingestions can severely injure the upper and lower aerodigestive tract, resulting in detrimental mucosal changes both acutely and chronically. Injuries are most severe following alkaline ingestion. Esophagectomy is often recommended…
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Prospective outcomes following drainless superficial parotidectomy with sternocleidomastoid flap reconstruction.
[BACKGROUND] Patients undergoing superficial parotidectomy for benign parotid lesions are at risk of postoperative complications, most notably cosmetic complications such as facial paralysis and contour defects, and functional complications…
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Open resection and reconstruction of a Nasoseptal Chondrosarcoma: case report and literature review.
[BACKGROUND] Primary chondrosarcomas of the nasal septum are rare, with a variety of clinical features that evade detection and treatment. While endoscopic surgery has become increasingly accessible, open approaches may be needed to provide…
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The Use of Botulinum Toxin Type A in the Healing of Thyroidectomy Wounds: A Randomized, Prospective, Placebo-Controlled Study.
[BACKGROUND] Recent research has indicated that botulinum toxin type A may have an inhibitory effect on the formation of fibroblasts and thus possibly decreases the severity of scar formation. Therefore, a trial was designed to assess the e…
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Submental liposuction for the management of lymphedema following head and neck cancer treatment: a randomized controlled trial.
[BACKGROUND] Patients who have undergone treatment for head and neck cancer are at risk for neck lymphedema, which can severely affect quality of life. Liposuction has been used successfully in cancer patients who suffer from post-treatment…