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23건 · 최신순-
Contemporary Indications and Technical Limits of Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.
Transoral laser microsurgery (TOLMS) is an established organ-preserving treatment for early-stage and selected intermediate-stage laryngeal squamous cell carcinoma (SCC). Initially indicated for Tis-T1 lesions, its use has progressively exp…
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Nomogram for Predicting Osteoradionecrosis After Fibula Free Flap for Mandibular Reconstruction.
[BACKGROUND] Osteoradionecrosis (ORN) is a severe complication following radiotherapy (RT), particularly after mandibular reconstruction with a fibula free flap. Risk prediction remains challenging due to limited data. [METHODS] We conduct…
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Surgical outcomes of profunda artery perforator flap in head and neck reconstruction: A systematic review and meta-analysis.
[OBJECTIVE] This study aims to evaluate the efficacy of the profunda artery perforator (PAP) flap in head and neck reconstruction. [METHODS] A single arm meta-analysis was performed for flap survival rate (primary outcome), reoperation for…
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Refining prognostic subcategories in intermediate-advanced glottic cancer: A multicentric study on 637 patients treated by transoral laser microsurgery.
[BACKGROUND] The current TNM staging system does not fully address the variations in glottic squamous cell carcinoma (SCC) extension and subsites involvement, especially if treated with transoral laser microsurgery (TOLMS). This study aims …
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Prognostic significance of surgical margins in laryngeal cancer treated by transoral laser microsurgery: a systematic review and meta-analysis.
[OBJECTIVE] To evaluate the prognostic significance of surgical margins in patients undergoing transoral laser microsurgery (TLM) for laryngeal squamous cell carcinoma (LSCC). [METHODS] A comprehensive literature search was conducted in Pu…
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Optimising oncologic outcomes in pT3 glottic cancers treated by transoral laser microsurgery: the impact of adjuvant treatment.
[OBJECTIVE] The treatment strategy for cT3 glottic squamous cell carcinoma (SCC) is far from being standardised, and the role of adjuvant treatment(s) is not clearly defined. This study assessed the impact of adjuvant (chemo-)radiotherapy (…
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Side-to-side characterisation of cellular content, soluble factors and in vitro potential on chondrocytes for bone marrow aspirate concentrate and adipose-derived stromal vascular fraction.
[PURPOSE] Orthobiologics gained popularity for the treatment of musculoskeletal pathologies, including osteoarthritis (OA). Bone marrow aspirate concentrate (BMAC) and adipose-derived stromal vascular fraction (SVF) were reported to reduce …
- Comments on: Value and role of surgical margins in transoral laser microsurgery of the larynx, literature review and clinical considerations.
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Enhancing quality of life in head and neck cancer patients: a comparative analysis of 3D exoscope-assisted surgery vs. traditional approaches.
[INTRODUCTION] The increasing population of survivors of head and neck carcinomas is becoming more conspicuous. Consequently, the pivotal role of quality of life, particularly elucidated through the assessment of dysphagia and dysphonia, is…
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Effectiveness of combined approach to recurrent respiratory papillomatosis (RRP).
[PURPOSE] Recent approaches for recurrent respiratory papillomatosis including local injection of bevacizumab and HPV vaccination show promise in reducing the need for frequent surgeries. In this study we propose a new combined approach of …
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The impact of margins in laryngeal cancer patients treated with transoral laser microsurgery: a systematic review and meta-analysis.
[PURPOSE] In laryngeal squamous cell carcinoma (LSCC) treated with transoral laser microsurgery (TOLMS), the status of margins significantly affected local control. When a positive or close margin is present, there is no ubiquitous consensu…
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Functional outcomes after transoral CO laser treatment for posterior glottic stenosis: a bicentric case series.
[PURPOSE] The aim of this study is to evaluate functional outcomes in terms of decannulation rate and quality of life of patients affected by PGS (Grades I-IV) treated only by transoral CO laser microsurgery (TOLMS) in two tertiary centers.…
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High-resolution US of the facial vessels with new facial vein landmarks for reconstructive surgery and dermal injection.
[BACKGROUND] Accurate knowledge of vessel anatomy is essential in facial reconstructive surgery. The technological advances of ultrasound (US) equipment with the introduction of new high-resolution probes improved the evaluation of facial a…
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Transoral Laser Microsurgery for Glottic Cancer in Patients Over 75 Years Old.
[OBJECTIVES/HYPOTHESIS] Laryngeal squamous cell carcinoma (LSCC) has a non-negligible incidence in elderly patients. However, there is still no clear indication on the ideal treatment for early-intermediate glottic LSCC in this specific age…
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Comprehensive Evaluation of Vocal Outcomes and Quality of Life after Total Laryngectomy and Voice Restoration with J-Flap and Tracheoesophageal Puncture.
[BACKGROUND] Tracheoesophageal puncture with a voice prosthesis is the gold standard for speech rehabilitation in patients that receive a laryngopharyngectomy. However, a novel surgical technique, using a tubularized anterolateral tight fla…
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Microsurgical procedures during COVID-19 pandemic: the VITOM® 3D-HD exoscopic system as alternative to the operating microscope to properly use personal protective equipment (PPE).
[PURPOSE] In the field of microsurgery, the use of conventional operating microscope, adopted in several disciplines, is not suitable with the full adoption of appropriate personal protective equipment (PPE), as goggles and face shields, ne…
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Validation of the European Laryngological Society classification of glottic vascular changes as seen by narrow band imaging in the optical biopsy setting.
[PURPOSE] In 2016, the European Laryngological Society (ELS) proposed a classification for vascular changes occurring in glottic lesions as visible by narrow band imaging (NBI), based on the dichotomic distinction between longitudinal vesse…
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Long-term Oncologic Outcomes of 1188 Tis-T2 Glottic Cancers Treated by Transoral Laser Microsurgery.
[OBJECTIVE] To evaluate long-term disease-specific survival (DSS) and organ preservation (OP) rates in patients affected by Tis-T2 glottic squamous cell carcinoma (SCC) treated by carbon dioxide transoral laser microsurgery (CO TOLMS). [ST…
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μRALP and Beyond: Micro-Technologies and Systems for Robot-Assisted Endoscopic Laser Microsurgery.
Laser microsurgery is the current gold standard surgical technique for the treatment of selected diseases in delicate organs such as the larynx. However, the operations require large surgical expertise and dexterity, and face significant li…
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Salvage carbon dioxide transoral laser microsurgery for laryngeal cancer after (chemo)radiotherapy: a European Laryngological Society consensus statement.
[PURPOSE] To provide expert opinion and consensus on salvage carbon dioxide transoral laser microsurgery (CO TOLMS) for recurrent laryngeal squamous cell carcinoma (LSCC) after (chemo)radiotherapy [(C)RT]. [METHODS] Expert members of the E…
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Quality of life after transoral CO laser posterior cordotomy with or without partial arytenoidectomy for bilateral adductor vocal cord paralysis.
[OBJECTIVES] Bilateral adductor vocal cord paralysis (BAVCP) is a rare and challenging condition whose main consequence is reduction of airway patency at the glottic level, often causing respiratory distress, while vocal function tends to r…
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Transoral laser microsurgery: feasibility of a new exoscopic HD-3D system coupled with free beam or fiber laser.
In the last decades, new technological devices and instruments have been developed to overcome the technical limits of transoral laser microsurgery. The recent introduction of 3D endoscopy seems to be a promising tool in the field of diagno…
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Imaging checklist for preoperative evaluation of laryngeal tumors to be treated by transoral microsurgery: guidelines from the European Laryngological Society.
[INTRODUCTION] The modern availability in daily practice of different DICOM viewers allows physicians to routinely evaluate computed tomography (CT) and magnetic resonance (MR) scans of patients in the pre-, intra-, and postoperative settin…