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Impact of Insurance Status on Postoperative Recovery after Microsurgical Breast Reconstruction.
Persistent disparities in breast reconstruction access have been widely documented, yet a significant research gap remains in understanding the impact of social determinants of health (SDOH) on postoperative outcomes and complications.A ret…
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Indocyanine green angiography predicts postoperative volume changes in deep inferior epigastric artery perforator flap breast reconstruction.
[BACKGROUND] Deep inferior epigastric artery perforator (DIEP) flaps are commonly used in breast reconstruction due to their muscle-sparing nature. However, postoperative volume changes can impact long-term breast symmetry. This study evalu…
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Therapeutic Modulation of the Nox2-Hv1-ROS Axis by Botulinum Neurotoxin A Confers Protection Against CoCl-Induced Retinal Hypoxic Injury.
Neuroinflammation and oxidative stress are key drivers of various ocular diseases. Experimental hypoxia, modeled using cobalt chloride (CoCl), induces hypoxia-inducible factor 1-alpha (HIF-1α) stabilization, mitochondrial dysfunction, and e…
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Do Abdominoplasties in Patients with Prior Sleeve Gastrectomy Impact De Novo Gastroesophageal Reflux Disorder and the Need for Conversion to Roux-en-Y Gastric Bypass?
The sleeve gastrectomy (SG) often requires conversion to Roux-en-Y gastric bypass (RYGB) due to gastroesophageal reflux disorder (GERD). Many postbariatric patients seek body-contouring surgery such as abdominoplasty to remove unwanted skin…
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Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors.
Bafilomycin A1, a vacuolar H-ATPase inhibitor, and botulinum toxin B and tetanus toxin, both vesicle fusion inhibitors, are widely known exocytosis blockers that have been used to inhibit the presynaptic release of neurotransmitters. Howeve…
- Successful Hair Transplantation for Scarring Alopecia Associated With Incontinentia Pigmenti.
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Stromal PTEN determines mammary epithelial response to radiotherapy.
The importance of the tumor-associated stroma in cancer progression is clear. However, it remains uncertain whether early events in the stroma are capable of initiating breast tumorigenesis. Here, we show that in the mammary glands of non-t…
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Comparative Analysis of Human Adipose-Derived Mesenchymal Stem Cells from Orbital and Abdominal Fat.
Adipose tissue contains abundant multipotent mesenchymal stem cells with strong proliferative and differentiating potential into adipocytes, osteocytes, and chondrocytes. However, adipose-derived mesenchymal stem cells (ASCs) showed variabl…
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Prolonged, acute suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants.
[UNLABELLED] We hypothesize that periodically early, local suppression of cysteinyl leukotrienes (CysLTs), which are potent inflammatory mediators, can reduce the fibrotic capsular contracture around silicone implants. We tested this hypoth…
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Acute suppression of TGF-ß with local, sustained release of tranilast against the formation of fibrous capsules around silicone implants.
We propose the acute, local suppression of transforming growth factor beta (TGF-ß), a major profibrotic cytokine, to reduce fibrosis around silicone implants. To this end, we prepared silicone implants that were able to release tranilast, a…
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Epidemiology of Oculoplastic and Reconstructive Surgeries Performed by a Single Specialist With 15 Years' Experience at a Tertiary Center.
[PURPOSE] To evaluate the prevalence of oculoplastic surgeries performed in a tertiary hospital in South Korea and to highlight the proper choice of surgery according to disease. [METHOD] Retrospective chart review was conducted over a 12-…
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Analysis of lower eyelid aging in an Asian population for customized lower eyelid blepharoplasty.
[PURPOSE] The objectives of this study were to evaluate the factors that contribute to aging in the lower eyelids and periorbital changes in Asians and to analyze the contribution of different anatomic factors before surgery. [METHODS] We …
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Gene expression signatures of morphologically normal breast tissue identify basal-like tumors.
[INTRODUCTION] The role of the cellular microenvironment in breast tumorigenesis has become an important research area. However, little is known about gene expression in histologically normal tissue adjacent to breast tumor, if this is infl…