Park H ⚠ 동명이인 가능성

Respiratory T cell immunity wanes rapidly, and inducing durable mucosal memory remains a major challenge. We demonstrate that precision adjuvant activity, using distinct pattern recognition receptor (PRR) agonists to shape innate inflammati…

Recent advances in gene network analysis have improved our understanding of complex disease mechanisms; however, interpreting estimated gene networks remains challenging. Existing methods for pathway enrichment analysis focus on gene sets a…

Acute myeloid leukemia (AML) is an aggressive hematological malignancy frequently exhibiting deregulated expression/activity/localization of the Wnt signaling mediator β-catenin. To derive more effective β-catenin targeting strategies, we p…

[BACKGROUND] Stemness-related marker expression in hepatocellular carcinomas (HCC) has been associated with aggressive behavior. The association between miRNA expression and HCC stemness remains unclear. [AIMS] To identify miRNAs associate…

Whilst T-cell directed therapies have revolutionized the therapeutic landscape in triple-class refractory multiple myeloma, ongoing long-term safety concerns remain, including the risk of second primary malignancy (SPM) development. We syst…

: Breast cancer is one of the most common malignancies, but its heterogeneous molecular subtypes make treatment decision-making complex and patient-specific. Both the pathology reports and the electronic medical record (EMR) play a critical…

Central nervous system (CNS) relapse in acute myeloid leukemia (AML) is uncommon but associated with poor outcomes. This retrospective study analyzed 960 AML patients who underwent hematopoietic cell transplantation (HCT) at Asan Medical Ce…

Myeloablative conditioning is standard for younger acute myeloid leukemia (AML) patients undergoing allogeneic hematopoietic cell transplantation (HCT), but optimal busulfan dosing remains unclear. We retrospectively analyzed 686 AML patien…

Identifying individual genomic characteristics is a critical focus in personalized therapies. To reveal targets in such therapies, we considered personalized gene network analysis using kernel-based -type regularization methods. In kernel-…

[PURPOSE] Conditional relative survival (CRS) estimates the probability of survival after surgery compared with the general population. We assessed 5-year CRS up to 5 years after gastric resection. [MATERIALS AND METHODS] We analyzed 15,60…

[INTRODUCTION] Increased metabolic activity is frequently observed in hepatocellular carcinoma (HCC). However, the impact of this increased metabolic activity on the efficacy of current treatments, such as the combination immunotherapy usin…

[INTRODUCTION] In secondary cleft lip and nasal deformity (CLND) correction, structural grafts are commonly used to control the nasal tip and restore the symmetry of the ala. However, the septal cartilage in Asians often weak and small. Bio…

[BACKGROUND]  The greatest challenge of a free-muscle transfer in facial reanimation surgery is anchoring muscle to perioral soft tissue. An additional incision provides a better way to anchor the transferred muscle but leaves a visible sca…

[BACKGROUND] A 1-2-mm thin rib cartilage graft was used as a septal extension graft to overcome the drawbacks of traditional rib cartilage rhinoplasty, which often results in a stiff nasal tip. The remaining rib cartilage was placed on the …

[OBJECTIVE] Thyrotropin (TSH) suppression therapy is a standard treatment after surgery for differentiated thyroid carcinoma (DTC). It may be associated with osteoporosis in postmenopausal women. However, there are no guidelines for bone mi…

[BACKGROUND] Because the tongue consists of 26 intrinsic and extrinsic muscles, even hemiglossectomy, which preserves some of the tongue and its muscles, leads to functional morbidity in speech and swallowing. Subsequent reconstruction usin…

[RATIONALE] Negative pressure pulmonary edema (NPPE) is associated with serious postoperative complications. Compact nasal packing is always done after an open rhinoplasty procedure which makes it difficult to achieve positive pressure vent…

[BACKGROUND] Reduced joint ROM and distraction-induced pain are common complaints of patients who have undergone gradual femoral lengthening. Attempts to reduce the effects of lengthening on joint motion have included the use of botulinum t…

[BACKGROUND] Asians characteristically have flat or broad and round facial features. These characteristics are primarily attributable to enlarged and widened jawbones, impressive muscles associated with mastication, and a zygomatic arch inv…