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Management of rare movement disorders in Europe: outcome of surveys of the European Reference Network for Rare Neurological Diseases.
[BACKGROUND AND PURPOSE] The diagnosis of rare movement disorders is difficult and specific management programmes are not well defined. Thus, in order to capture and assess care needs, the European Reference Network for Rare Neurological Di…
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Unilateral pallidal stimulation for disabling dystonia due to Rasmussen's disease.
[OBJECTIVE] To describe an adult patient with Rasmussen's disease with focal dystonia as the most disabling symptom and the good response to unilateral globus pallidus internus (GPi) deep brain stimulation (DBS). [METHODS] Retrospective re…
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[Cost-utility analysis of two formulations of botulinum toxin type A in the treatment of blepharospasm and cervical dystonia in Spain].
[INTRODUCTION] Studies on focal dystonia showed that the formulations of botulinum toxin type A, incobotulinumtoxin-A (Inco-BTA) and onabotulinumtoxin-A (Ona-BTA), have equivalent efficacy and safety. [AIM] To carry-out a cost-utility anal…
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Clinical Practice: Evidence-Based Recommendations for the Treatment of Cervical Dystonia with Botulinum Toxin.
Cervical dystonia (CD) is the most frequent form of focal dystonia. Symptoms often result in pain and functional disability. Local injections of botulinum neurotoxin are currently the treatment of choice for CD. Although this treatment has …
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Neutralizing Antibody and Botulinum Toxin Therapy: A Systematic Review and Meta-analysis.
The formation of neutralizing antibodies (NAbs) directed specifically against the active neurotoxin part of the botulinum neurotoxin (BoNT) complex is often cited as a major cause of secondary non-responsiveness (SnR) to treatment. This sys…
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Practical guidance for CD management involving treatment of botulinum toxin: a consensus statement.
Cervical dystonia is a neurological movement disorder causing abnormal posture of the head. It may be accompanied by involuntary movements which are sometimes tremulous. The condition has marked effects on patients' self-image, and adversel…