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Combining Historic and Modern Concepts: How the Delay Phenomenon Enhances Propeller Flap Success in Large Dorsolumbar Soft Tissue Reconstruction.
The authors present a novel 2-staged approach for complex dorsolumbar wound reconstruction in a multioperated spine patient with limited local flap options and contraindications for free flap reconstruction due to arteriosclerosis and cardi…
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Intramuscular Microvascular Flow Sensing for Flap Monitoring in a Porcine Model of Arterial and Venous Occlusion.
[BACKGROUND] Commercially available near infrared spectroscopy devices for continuous free flap tissue oxygenation (StO) monitoring can only be used on flaps with a cutaneous component. Additionally, differences in skin quality and pigment…
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Single-Cell Surgery and Intracellular Organelle Manipulation Via Thermoplasmonics Combined Optical Trapping.
Microsurgery and biopsies on individual cells in a cellular microenvironment are of great importance to better understand the fundamental cellular processes at subcellular and even single-molecular levels. However, it is still a big challen…
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Intramuscular Near-Infrared Spectroscopy for Muscle Flap Monitoring in a Porcine Model.
[BACKGROUND] Current near-infrared spectroscopy (NIRS)-based systems for continuous flap monitoring are limited to flaps which carry a cutaneous paddle. As such, this useful and reliable technology has not previously been applicable to mus…
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Implantable, wireless, self-fixing thermal sensors for continuous measurements of microvascular blood flow in flaps and organ grafts.
Vascular pedicle thrombosis after free flap transfer or solid organ transplantation surgeries can lead to flap necrosis, organ loss requiring re-transplantation, or even death. Although implantable flow sensors can provide early warning of …
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Aberrant methylation of the maspin promoter is an early event in human breast cancer.
The maspin gene functions as a tumor suppressor in human breasts, and its expression is frequently lost during breast cancer progression. In vitro models of human breast cancer indicate that the loss of maspin expression is closely linked t…