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6건- A prospective, exploratory study of F-PSMA-1007 PET/CT in patients with medullary thyroid cancer.
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Trends in the Incidence, Organization of Care, and Surgical Treatment of Medullary Thyroid Cancer: A Population-Based Study.
Medullary thyroid cancer (MTC) is a rare cancer with variable disease course. To enable optimal care, centralization and consensus guidelines are essential. This study describes trends in the incidence, organization of care, surgical treatm…
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Validation of the International Medullary Thyroid Cancer Grading System and Identification of EZH2 as a Prognostic and Potential Therapeutic Marker in Medullary Thyroid Cancer.
Medullary thyroid cancer (MTC) is a heterogeneous disease. While the International MTC Grading System (IMTCGS) provides baseline risk stratification, it lacks therapeutic relevance. In several cancers, EZH2 overexpression harbors an adverse…
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The value of F-FDG PET/CT and F-DOPA PET/CT in determining the initial surgical strategy of patients with medullary thyroid cancer : Preoperative PET/CT imaging for medullary thyroid cancer.
[BACKGROUND] While total thyroidectomy with central neck dissection (CND) is standard for medullary thyroid cancer (MTC), performing a lateral neck dissection (LND) depends on locoregional metastatic spread and is usually decided per indivi…
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The utility of Ga-DOTATATE and F-FDG PET/CT in predicting the response to tyrosine kinase inhibitors in patients with advanced medullary thyroid cancer.
[BACKGROUND] Tyrosine kinase inhibitors (TKIs) have significantly improved the prognosis of patients with advanced medullary thyroid cancer (MTC). However, treatment response heterogeneity leads to challenges in predicting individual favour…
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Patient-derived medullary thyroid cancer organoids: a potential model for mechanistic studies on diagnostics and therapy.
[OBJECTIVE] Medullary thyroid carcinoma (MTC) is a rare neuroendocrine thyroid tumor, with only 30 new patients annually in the Netherlands. PET imaging provides information on distant metastases, after which tyrosine kinase inhibitors (TKI…