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22건 · 최신순-
Immunomodulation in healing: neoadjuvant immunochemotherapy reduces major wound complications and accelerates recovery in oral cancer surgery.
[BACKGROUND] Major wound complications after oral squamous cell carcinoma surgery remain a significant cause of morbidity, delaying adjuvant therapy and impairing recovery. Neoadjuvant immunochemotherapy may improve pathological responses, …
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Comparison of the clinical efficacy of different acupuncture methods in the treatment of post-stroke central facial paralysis-a network meta-analysis based on randomized controlled trials.
[BACKGROUND] Post-stroke central facial paralysis (CFP) is a common post-stroke complication that affects the quality of life. The current conventional treatment has limitations in efficacy and safety. As a traditional medical therapy, acup…
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Septoaponeurotic Junctional Thickening Fixation Technique in 13,500 Asian Upper Blepharoplasties: Evidence-Based Outcomes Driving Technical Refinement.
[BACKGROUND] To evaluate the anatomical rationale and clinical efficacy of septoaponeurotic junctional thickening (SAJT) fixation technique in Asian upper blepharoplasty. [METHODS] Retrospective analysis of 13,500 consecutive cases (12,150…
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Ocular surface side effects of botulinum toxin type A injections in the treatment of lateral canthal wrinkles (Crow's Feet).
[PURPOSE] This study investigates the impact of Botulinum Toxin Type A (BoNT-A) injections for lateral canthal wrinkles on the ocular surface. [METHODS] A total of 30 patients (30 eyes) who received BoNT-A injections were followed over a t…
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Clinical impacts of botulinum toxin type A injections for provoked vestibulodynia: insights from randomized controlled trials.
[BACKGROUND] Provoked vestibulodynia (PVD) is a chronic vulvar pain condition often associated with pelvic floor muscle hypertonicity. Botulinum neurotoxin type A (BoNT-A), a neuromuscular transmission blocker, has been proposed as a potent…
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Clinical Application of the High Superficial Musculoaponeurotic System for Facial Rejuvenation in Chinese Patients.
[BACKGROUND] Face lift surgery can improve facial sagging and reestablish a youthful relationship between the soft tissues and the underlying skeleton. The early manifestations of aging in the periorbital region include sagging of the later…
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Association of preoperative aneurysmal wall enhancement with relief of chronic headache after surgical clipping of unruptured intracranial aneurysms.
[OBJECTIVE] To investigate the association between chronic headache outcome and aneurysmal wall enhancement (AWE) on high-resolution vessel wall imaging (HR-VWI) in patients with unruptured intracranial aneurysms (UIAs) who underwent micros…
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Efficacy and safety of botulinum toxin A in the treatment of female pattern hair loss.
[BACKGROUND] Female pattern hair loss (FPHL) is the most prevalent type of alopecia among adult women. Presently, topical minoxidil stands as the sole treatment endorsed by the FDA. Addressing cases of FPHL in individuals who develop contac…
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S-Nitrosylation of Septin2 Exacerbates Aortic Aneurysm and Dissection by Coupling the TIAM1-RAC1 Axis in Macrophages.
[BACKGROUND] S-Nitrosylation (SNO), a prototypic redox-based posttranslational modification, is involved in cardiovascular disease. Aortic aneurysm and dissection are high-risk cardiovascular diseases without an effective cure. The aim of t…
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The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta-analysis of randomized controlled trials.
This study aimed to assess the effectiveness and safety of botulinum toxin (BTX) injections for managing motor disorders in patients with Parkinson's disease (PD). An electronic search was conducted based on Preferred Reporting Items for Sy…
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Temporal Incision Super-high Superficial Musculoaponeurotic System Face Lift for Chinese Patients.
[BACKGROUND] This investigation assessed patient satisfaction with a temporal incision technique using a super-high superficial musculoaponeurotic system (SMAS) flap for midface lifting in a Chinese patient cohort. [METHODS] From July 2019…
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The efficacy and safety of intra-articular botulinum toxin type A injection for knee osteoarthritis: A meta-analysis of randomized controlled trials.
The purpose of this study was to investigate the efficacy and safety of intra-articular Botulinum Toxin type A (BTA) injection in the management of patients with knee osteoarthritis (KOA). The literature retrieval was conducted based on PRI…
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Dynamically monitoring lymphatic and vascular systems in physiological and pathological conditions of a swine model via a portable NIR-II imaging system with ICG.
NIR-II imaging with indocyanine green (ICG) has been clinically used in liver tumor resection. However, few data are available concerning the application of ICG-NIR-II in lymphatic and vascular systems in clinic. To expand the application a…
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Nexinhib20 Inhibits Neutrophil Adhesion and β Integrin Activation by Antagonizing Rac-1-Guanosine 5'-Triphosphate Interaction.
Neutrophils are critical for mediating inflammatory responses. Inhibiting neutrophil recruitment is an attractive approach for preventing inflammatory injuries, including myocardial ischemia-reperfusion (I/R) injury, which exacerbates cardi…
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Case report and literature review: Malignant adenomyoepithelioma after breast augmentation.
[BACKGROUND] Breast malignant adenomyoepithelioma (MAME) after breast augmentation has never been reported. [CASE SUMMARY] We reported a case of a 55-year-old woman who was diagnosed with breast MAME 16 years after breast augmentation. Bre…
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Profiling gene expression reveals insights into pulmonary response to aerosolized botulinum toxin type A exposure in mice.
Botulinum neurotoxin type A (BoNT/A) is traditional medicine and well known for its therapeutic use as an anesthetic and in cosmetic applications that work through the inhibition of acetylcholine exocytosis in neuronal cells. BoNT/A also ha…
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A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report.
[INTRODUCTION] Arginineemia, also known as arginase deficiency, is a rare autosomal recessive metabolic disease. The diagnosis sometimes may be delayed due to atypical clinical manifestations. Confirmation of arginineemia depends on genetic…
- Reply: Effects of Botulinum Toxin on Improving Facial Surgical Scars: A Prospective, Split-Scar, Double-Blind, Randomized Controlled Trial.
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Botulinum toxin type A suppresses arterial vasoconstriction by regulating calcium sensitization and the endothelium-dependent endothelial nitric oxide synthase/soluble guanylyl cyclase/cyclic guanosine monophosphate pathway: An study.
[UNLABELLED] Botulinum toxin type A (BTX-A) is a potent neurotoxin that causes relaxation of striated muscle by inhibiting the release of acetylcholine at the neuromuscular junction. Some studies have suggested that BTX-A treatment for Rayn…
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Effects of Botulinum Toxin on Improving Facial Surgical Scars: A Prospective, Split-Scar, Double-Blind, Randomized Controlled Trial.
[BACKGROUND] Early intervention might improve the quality of surgical scars. Botulinum toxin type A has been shown to improve surgical scars in the past decade. The purpose of this study was to evaluate the effect of botulinum toxin type A …
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Intra-articular injection of Botulinum toxin A reduces neurogenic inflammation in CFA-induced arthritic rat model.
Currently, administration of Botulinum toxin Type A (BoNT/A) to treat arthritic pain has promising efficacy in clinical research. However, the mechanisms underlying anti-neurogenic inflammation mediated by BoNT/A remains unclear. The aim of…
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Treatment of axillary bromhidrosis through a mini-incision with subdermal vascular preservation: a retrospective study in 396 patients.
[BACKGROUND] Axillary bromhidrosis is a condition presenting as malodor caused by an interaction between the discharge of apocrine glands and bacteria. Topical agents, liposuction, and elective surgery are currently the main therapeutic mod…