논문 목록
11건-
Diagnostic performance of ultrasonography in predicting extrathyroidal extension in papillary thyroid carcinoma.
[INTRODUCTION] Extrathyroidal extension (ETE) is a critical prognostic factor influencing treatment decisions in papillary thyroid carcinoma (PTC). While ultrasonography (US) is widely used for preoperative ETE assessment, its diagnostic ac…
-
Discovery of a predictive model for anlotinib-induced hand-foot syndrome based on metabolomics.
The purpose of this study was to investigate the exposure-toxicity relationship between anlotinib (ANL) and the hand-foot syndrome (HFS) and to establish an early warning model of ANL-induced HFS based on exposure level and metabolomics. Th…
-
Hotspots and future trends of male breast cancer: a global perspective.
[BACKGROUND] Male breast cancer (MBC), a rare disease accounting for less than 1% of all cancers in men and approximately 1% of all breast cancers globally, exhibits unique biological and clinical characteristics that distinguish it from fe…
-
Thermosensitive hydrogel-enhanced RPA-CRISPR/Cas12a biosensor for ultrasensitive detection of methylated loci in breast cancer ctDNA.
[BACKGROUND] Methylation differences exist between breast cancer tissues and normal tissues. The release of methylated circulating tumor DNA (ctDNA) by tumor cells provides a foundation for breast cancer liquid biopsy using methylated ctDNA…
-
Medium-chain fatty acids activate fructose metabolism via up-regulating GLUT5-KHK axis.
Fructose is an abundant monosaccharide in the human diet and an important source of energy in the human body. GLUT5, a member of facilitative glucose transporter family, is the only membrane transporter that specifically transports fructose…
-
Anxiety in breast cancer research (1982-2024): a bibliometric analysis.
[BACKGROUND] Breast cancer remains a major global malignancy, with anxiety severely impacting patients' quality of life and treatment outcomes. Understanding evolving research trends is critical for developing effective interventions. This …
-
Explainable machine learning model predicts response to adjuvant therapy after radical cystectomy in bladder cancer.
[PURPOSE] Radical cystectomy (RC) is the standard treatment for muscle-invasive and select high-risk non-muscle-invasive bladder cancer. Despite definitive surgery, recurrence and progression remain major clinical concerns. Adjuvant chemoth…
-
Lactylated histone H3K18 as a potential biomarker for the diagnosis and prediction of the severity of pancreatic cancer.
[BACKGROUND] Lactylation plays an essential role in pancreatic cancer, but the precise role of lactylated histone in the diagnosis and prognosis of pancreatic cancer remains to be further clarified. [METHODS] Twenty-one patients diagnosed …
-
[Corrigendum] Reactive oxygen species‑mediated activation of the Src‑epidermal growth factor receptor‑Akt signaling cascade prevents bortezomib‑induced apoptosis in hepatocellular carcinoma cells.
Following the publication of the above article, the authors have realized that there were several duplicated western blots featured in Figs. 2‑4. The EGFR blot correctly presented for Fig. 3 (the HepG2 cell line) had been inadvertently feat…
-
Can radiotherapy be omitted in T1-2N1 breast cancer patients after mastectomy without neoadjuvant therapy?
[OBJECTIVE] To evaluate the necessity of postmastectomy radiotherapy (PMRT) in patients with T1-2N1M0 breast cancer who did not receive neoadjuvant therapy, by assessing its impact on locoregional recurrence (LRR) and overall survival (OS) …
-
The Combination of Tunnel Shaped Excision with Radiotherapy and Injection of Type A Botulinum Toxin in the Treatment of Auricular Keloids.
[BACKGROUND] To investigate the clinical effect of the combination of tunnel shaped excision with radiotherapy and injection of type A botulinum toxin in the treatment of auricular keloids. [METHODS] From June 2017 to May 2023, a total of …