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Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ.
[INTRODUCTION] Basal-like and luminal breast cancers have distinct stromal-epithelial interactions, which play a role in progression to invasive cancer. However, little is known about how stromal-epithelial interactions evolve in benign and…
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Interlobular and intralobular mammary stroma: genotype may not reflect phenotype.
[BACKGROUND] The normal growth and function of mammary epithelial cells depend on interactions with the supportive stroma. Alterations in this communication can lead to the progression or expansion of malignant growth. The human mammary gla…