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Temporal Trends in Clinicopathological Features and Outcomes of De Novo Metastatic Luminal A Breast Cancer: A Retrospective Multicenter Analysis (2017-2025).
Whether clinicopathological features of de novo Luminal A metastatic breast cancer (MBC) have evolved across recent diagnostic periods remains unclear. In this retrospective, multicenter cohort study, we evaluated temporal changes in tumor …
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The Role of Body Mass Index in Determining the Efficacy of Nivolumab for Patients with Advanced Non-Small Cell Lung Cancer.
BACKGROUND Non-small cell lung cancer (NSCLC) comprises 85% of lung cancers with poor prognosis. Immune checkpoint inhibitors (ICIs), particularly nivolumab, show survival benefits in advanced NSCLC. The effect of body mass index (BMI) on i…
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CEA and CA 19-9 combined tumor marker index as a prognostic tool for metastatic pancreatic cancer: is two better than one?
Metastatic pancreatic cancer (PC) is one of the cancers with the worst prognosis, and prognostic tests are lacking in this population. If an effective prognostic indicator can be identified, the patient population can be monitored more clos…