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Are venous thromboembolism risk assessment tools reliable in the stratification of microvascular risk following lower extremity reconstruction?
[INTRODUCTION] The incidence of flap failure is significantly higher in the lower extremity compared to free tissue transfer in the head, neck and breast. The most common cause of flap failure is venous thrombosis. The aim of this study was…
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Functional significance of active site residues in the enzymatic component of the binary toxin.
binary toxin (CDT) is an ADP-ribosyltransferase which is linked to enhanced pathogenesis of strains. CDT has dual function: domain (CDTa) catalyses the ADP-ribosylation of actin (enzymatic component), whereas domain (CDTb) transports CDT…