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Inter-Individual Variation in Response to Estrogen in Human Breast Explants.
Exposure to estrogen is strongly associated with increased breast cancer risk. While all women are exposed to estrogen, only 12% are expected to develop breast cancer during their lifetime. These women may be more sensitive to estrogen, as …
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Paralemmin-1 is over-expressed in estrogen-receptor positive breast cancers.
[BACKGROUND] Paralemmin-1 is a phosphoprotein lipid-anchored to the cytoplasmic face of membranes where it functions in membrane dynamics, maintenance of cell shape, and process formation. Expression of paralemmin-1 and its major splice var…