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CancerSubminer: an integrated framework for cancer subtyping using supervised and unsupervised learning on DNA methylation profiles.
Human cancer is highly heterogeneous, resulting in variable drug resistance and clinical outcomes. This complexity hinders accurate prognosis prediction and the development of targeted therapies. Molecular subtyping addresses these challeng…
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Effectiveness of Intraoperative Ketorolac in Outpatient Breast Surgery: A Double-blinded Prospective Randomized Controlled Trial.
[BACKGROUND] The use of nonnarcotic analgesics, such as ketorolac, has been shown to reduce postoperative pain and opioid consumption. This double-blinded randomized trial is designed to assess the efficacy of intraoperative ketorolac in re…
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Usefulness of Free Tissue Transfer for the Reconstruction of Extensive Thigh Defects.
[BACKGROUND] Despite the increasing popularity of free tissue transfer, thigh defects have been alienated from their potential indication, owing to the abundance of regional reconstruction options. However, some challenging situations wher…
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Klebsiella Aerogenes Infection on the Costochondral Graft of the Nose.
Klebsiella aerogenes is a nosocomial and pathogenic bacterium that causes opportunistic infections including most types of infections. After rhinoplasty, the inserted costochondral graft could be a good material for bacterial growth due to …