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Antiproliferative and antimigratory activities of bisphosphonates in human breast cancer cell line MCF-7.
Bisphosphonates (BPs) are antiresorptive drugs that act as effective inhibitors of cancer cell proliferation. However, not all bisphosphonates are equally effective against breast cancer cells . The present study investigated the extent to …
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Inhibition of growth and migration of cholangiocarcinoma cells by pamidronate.
Pamidronate has been hypothesized to effectively inhibit cancer cell growth and metastasis in bone tissue. Furthermore, pamidronate (Pami) exerts various direct effects against several cancer cell types, including growth and migration. The …
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Cytotoxic and antimigratory effects of extract against HepG2 liver cancer cells.
The aim of the present study was to investigate the molecular mechanisms underlying (CF) Dyer-induced cancer cell death and antimigratory effects in HepG2 liver cancer cells. The cytotoxic, antiproliferative and antimigratory effects of CF…
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Simvastatin potentiates doxorubicin activity against MCF-7 breast cancer cells.
Simvastatin is a low density lipoprotein-lowering drug that is widely used to prevent and treat cardiovascular disease by inhibiting the mevalonate pathway. Simvastatin also exhibits inhibitory effects on a number of types of cancer. In the…