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Better pancreatic adenocarcinoma outcomes linked to anti-EBV TCR CDR3 detection via tumor RNAseq files.
Although the Epstein-Barr virus (EBV) is implicated in several cancer types, its potential role in the initiation and progression of pancreatic cancer remains poorly understood. In this study, T-cell receptor (TCR) complementarity-determini…
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Higher chemical complementarity of EBV epitopes and IGH CDR3s correlates with better outcomes for lymphoma and ovarian cancer.
This study investigated the relationship between Epstein-Barr virus (EBV) epitopes and tumor-resident immunoglobulin heavy chain (IGH) CDR3 amino acid (AA) sequences sourced from cancers with a link to EBV. In the case of ovarian cancer, th…