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19건 · 최신순-
Electromyography-guided botulinum toxin injections in provoked vestibulodynia: a randomized double-blind placebo-controlled clinical trial.
[BACKGROUND] Provoked vestibulodynia is a prevalent and complex disease with a major effect on women's quality of life. This condition is often associated with abnormal reflexes and muscle hypertonicity. Local injections of Onabotulinum tox…
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Clinical and urodynamic benefit of adding antimuscarinics after a loss of efficacy of intradetrusor botulinum toxin in patients with multiple sclerosis.
[PURPOSE] The aim was to assess in real-life practice the effectiveness of adding antimuscarinics drug (AM) when facing a loss of efficacy of intradetrusor botulinum toxin A (IDBTX-A) in patients with multiple sclerosis (PwMS) on overactive…
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Intrarectal Injections of Botulinum Toxin for the Treatment of Urge Fecal Incontinence: Long-Term Results of an FI-Toxin Cohort Study.
[BACKGROUND] The efficacy and safety of intrarectal botulinum toxin A (BoNT/A) injections in patients with urge fecal incontinence (FI) were evidenced in a large, multicenter, randomized, placebo-controlled study (FI-TOXIN). The aims of the…
- Correction: Clinical and urodynamic benefit of adding antimuscarinics after a loss of efficacy of intradetrusor botulinum toxin in patients with multiple sclerosis.
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Effect on sensory and motor parameters of a first intradetrusor botulinum neurotoxin A injection in patients with neurogenic bladder: A retrospective study.
[BACKGROUND] Overactive bladder (OAB) is common in suprasacral neurological disorders and often associated with detrusor overactivity (DO). Botulinum neurotoxin A (BoNT-A) is a second-line treatment inducing reversible chemical denervation.…
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Intrarectal injections of botulinum toxin versus placebo for the treatment of urge faecal incontinence in adults (FI-Toxin): a double-blind, multicentre, randomised, controlled phase 3 study.
[BACKGROUND] Non-randomised studies assessing intrarectal botulinum toxin type A (BoNTA) injections for faecal incontinence are promising. We aimed to evaluate the efficacy of BoNTA for the treatment of faecal incontinence in a randomised s…
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How to define failure of intradetrusor injections of botulinum toxin A for neurogenic detrusor overactivity.
[INTRODUCTION] Neurogenic detrusor overactivity (NDO) has a major impact on patients' quality of life and can lead to upper urinary tract complications. Intradetrusor botulinum toxin type A injections are administered as second-line treatme…
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[Guidelines on the urological management of the adult patient with spinal dysraphism (spina bifida)].
[INTRODUCTION] Improved life expectancy and prenatal screening have changed the demographics of spina bifida (spinal dysraphism) which has presently become a disease of adulthood. Urinary disorders affect almost all patients with spinal dys…
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Efficacy and safety of intradetrusor botulinum toxin injections for idiopathic overactive bladder syndrome in patients with an artificial urinary sphincter.
[PURPOSE] To assess the efficacy and safety of intradetrusor botulinum toxin type A injections (IBTI) for idiopathic overactive bladder (iOAB) in non-neurological adults with an artificial urinary sphincter (AUS). [MATERIALS AND METHODS] W…
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[Urinary disorders of Wolfram syndrome. Clinical and urodynamic analysis from 6 observations].
[UNLABELLED] Wolfram syndrome is a neurodegenerative disorder characterized by childhood onset diabetes mellitus, optic nerve atrophy, diabetes insipidus, hearing impairment, brainstem alteration and commonly bladder and bowel dysfunction. …
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Nocturia in Patients With Multiple Sclerosis.
The prevalence of nocturia in patients with multiple sclerosis (MS) is high, ranging from 20.9% to 48.8% in this population. Its underlying pathophysiology is complex and different from the non-neurogenic population. In the MS population, t…
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[Use of botulinum toxin A in pelvic floor dysfunctions in the elderly: A review].
[INTRODUCTION] The present article is the final report of a multi-disciplinary meeting supported by the GRAPPPA (group for research applied to pelvic floor dysfunctions in the elderly). The objective was to conduct a comprehensive review on…
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[Efficacy of botulinum toxin A injections in the urethral sphincter in patients with difficulties to perform self-intermittent catherization].
[PURPOSE] To evaluate safety and efficacy of botulinum toxin A injections in the urethral striated sphincter in patients with difficulties to perform self-intermittent catherization. [METHODS] In this prospective study, 12 patients sufferi…
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Adherence to Anticholinergic Therapy and Clean Intermittent Self-Catheterization in Patients With Multiple Sclerosis.
[PURPOSE] To evaluate adherence to anticholinergic therapy (AT) and clean intermittent self-catheterization (CISC) in patients with multiple sclerosis (MS) and to identify factors associated with poor adherence. [METHODS] This single-cente…
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Emptying cystometry: A feasibility and validation pilot study on female patients.
[INTRODUCTION] To assess the feasibility and the accuracy of emptying cystometry in order to simplify the manometric follow-up of overactive detrusor in neurological patients under anticholinergic or botulinum toxin injections. [MATERIAL] …
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Intradetrusor Injections of Botulinum Toxin A in Adults with Spinal Dysraphism.
[PURPOSE] The aim of the current study was to determine the outcomes of botulinum toxin A intradetrusor injections in adult patients with spina bifida. [MATERIALS AND METHODS] All patients with spinal dysraphism who underwent intradetrusor…
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Efficacy and safety of two administration modes of an intra-detrusor injection of 750 units dysport® (abobotulinumtoxinA) in patients suffering from refractory neurogenic detrusor overactivity (NDO): A randomised placebo-controlled phase IIa study.
[AIMS] Assess the efficacy and safety of abobotulinumtoxinA (Dysport®) in adult patients with neurogenic detrusor overactivity (NDO). [METHODS] This Phase IIa, international, multicentre, double-blind, randomised, placebo controlled, pilot…
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Intermittent catheterization difficulty questionnaire (ICDQ): A new tool for the evaluation of patient difficulties with clean intermittent self-catheterization.
[AIMS] Once a catheterization technique has been learned and acquired, psychological barriers have been overcome and a specific catheter has been selected, a patient will need to use clean intermittent self-catheterization (CISC) on a long-…
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[Definition of botulinum toxin failure in neurogenic detrusor overactivity: Preliminary results of the DETOX survey].
[OBJECTIVE] There is currently no guideline regarding the management of neurogenic detrusor overactivity (NDO) refractory to intra-detrusor botulinum toxin injections. The primary objective of the present study was to find a consensus defin…